Citrate, bisglycinate, malate, threonate, oxide, chloride, taurate, lactate. If you have recently looked for a magnesium supplement, you have come across this list. Each bottle promises different things and almost all seem the same at first glance.
The truth is that they are not interchangeable. Each form magnesium has an absorption, a target, and a profile of effects different side effects. Taking bisglycinate when what you need is citrate is like taking paracetamol hoping to sleep better: the active ingredient active is magnesium in both cases, but the effect and the target organ change.
If what you want to know is what magnesium does in general, the chart completo está en para qué sirve el magnesium. This guide is specific: the 8 main forms of market, what each one does better and which to choose according to your goal specific.
| Form | Best for | Absorption | Digestive tolerance |
|---|---|---|---|
| Bisglycinate | Sleep, anxiety, cramps | High | Excellent |
| Citrate | Constipation, general sports | High | Good (can loosen) |
| Malate | Chronic fatigue, fibromyalgia | High | Good |
| Threonate (L-threonate) | Memory, brain function | High | Good |
| Taurate | Cardiovascular, blood pressure | High | Good |
| Glycinate | Stress, deep sleep | High | Excellent |
| Chloride | Severe deficiency, transdermal | Medium | Variable |
| Oxide | The best-selling — and the least absorbable | Very low | Can cause diarrhea |
Which magnesium according to your goal?
Choose what you want to achieve and we tell you the form, dose, and time of day
Why the chemical form of magnesium matters so much
Pure magnesium (Mg²⁺) is not sold as a supplement. What is sold is magnesium bound to another molecule (an anion) that transports it to the body and releases it where it needs to act. That molecule transporter conditions three things:
- How much magnesium is absorbed in the intestine (bioavailability)
- Where that magnesium goes once absorbed (target tissue) target)
- What side effects does the combination have (digestion, drowsiness, energy)
The difference between two forms of magnesium can be so great that one absorbs 30% and another 4%. That is why the choice of type is not trivial: you are deciding whether your body takes advantage of the supplement or if the most of it passes through the stool without having done its job.
Bisglycinate (or glycinate): the most versatile general-use one
Magnesium bound to two glycine molecules, an amino acid. The combination has three advantages:
- Very high absorption because glycine acts as a efficient transporter
- Excellent digestive tolerance: practically never causes diarrhea
- Calming effect because glycine itself is a inhibitory neurotransmitter
It is considered the "all-terrain" form of magnesium. If you are only going to have a magnesium supplement at home and you don't know exactly what you need it for, bisglycinate covers 80% of cases.
When to choose it specifically: - Problems with sleep or mild insomnia - Anxiety, chronic stress, muscle tension - Muscle cramps (including athletes) - Digestive sensitivity with other supplements - Women in perimenopause with sleep fragmented
Typical dose: 200-400 mg of elemental magnesium per at night.
Citrate of magnesium: the most efficient for sports and digestion
Magnesium bound to citric acid. It is the most studied form and the one more often recommended in conventional medical consultations. Its profile:
- High absorption (similar to bisglycinate)
- Mild to moderate laxative effect: helps with transit
- Excellent for general sports due to the combination with citrate (which helps the Krebs cycle)
When to choose it specifically: - Constipation chronic or slow transit - Athletes who sweat a lot and want to replenish minerals - Post-workout muscle cramps - People with kidney stones kidney stones from oxalate (citrate helps prevent their formation)
When to avoid it: - If you tend to have soft stools soft stools or irritable bowel syndrome with diarrhea - At high doses, may cause soft stools
Typical dose: 200-400 mg of elemental magnesium per day, in one or two doses.
Malate: the ally against chronic fatigue
Magnesium bound to malic acid, an organic acid found in fruits. The distinctive feature is the combination: malic acid participates in the of Krebs cycle, the cellular machinery that produces energy. This makes malate has a subjective “energizing” effect on people with fatigue chronic.
- High absorption
- Good effect on energy and endurance
- Well tolerated at high doses
When to choose it specifically: - Chronic fatigue, fibromyalgia - People with persistent morning fatigue - General muscle sensitivity - Athletes during high load periods load
Typical dose: 300-600 mg of elemental magnesium per day, preferably in the morning or split between morning and noon. At night it can cause too much activation in sensitive people sensitive.
Threonate (L-threonate): the only one that crosses the blood-brain barrier
Relatively recent form (patent from 2010). Magnesium bound to L-threonate, a metabolite of vitamin C. Its distinctive feature is unique in el mercado: es la única forma de magnesio que cruza la barrera blood-brain barrier with significant efficacy, allowing it to reach the cerebrospinal fluid and increase brain magnesium.
- High and specific absorption to the brain
- Promising studies on cognitive function and memory
- More expensive than other forms (3-5 times the price of a bisglycinate)
When to choose it specifically: - Problems with memory or concentration - Older adults with mild cognitive decline - Tasks with high sustained cognitive load - Support during periods intensive study
When it’s not worth it: - If your goal is sports, digestive or sleep: any other form gives the same or better result for less price.
Typical dose: 1,000-2,000 mg of magnesium L-threonate per day (equivalent to 144-288 mg of elemental magnesium), divided into 2-3 doses.
Taurate: the specific for the cardiovascular system
Magnesium bound to taurine, an amino acid with cardioprotective effect documented. The combination preferentially concentrates in tissue cardiac and vascular.
- High absorption
- Synergistic effect with taurine on blood pressure arterial and heart rhythm
- Less common form in the European market
When to choose it specifically: - Mild hypertension or tendency - Mild cardiac arrhythmias (always with medical approval) - People with family history of cardiovascular issues - Support for cardiovascular improvement programs
Typical dose: 200-400 mg of elemental magnesium per day.
Magnesium chloride: the one for transdermal use
Magnesium bound to chloride. Historically popular as “sea water” or Epsom salt. The transdermal form (applied on skin) has its niche, although the evidence of absorption through the skin is modest. Transdermal route oral, causes more digestive problems than bisglycinate or citrate.
- Acceptable oral absorption but worse than previous
- Useful in baths or local muscle application
- Intense salty taste if taken diluted in water
When to choose it specifically: - Recovery local muscle through baths (Epsom salts) - Topical application directly on the painful area - As a supplement, not as a source main
Typical oral dose: 200-400 mg per day. Topical: according to product.
Oxide of magnesium: the best-selling and least effective
The one that fills pharmacies and supermarkets. It’s cheap because the manufacturing process is simple. It’s popular because the bottle usually indicate high doses (500-800 mg) that seem like a lot for little dinero. Pero la absorción real es muy baja: alrededor del 4-10% of the magnesium in the bottle reaches the bloodstream.
- Very low absorption
- Strong laxative effect: most of the magnesium remains in the intestine and attracts water
- Useful only as an occasional laxative
When it makes sense: - Acute occasional constipation - Intestinal cleansing before a colonoscopy (with prescription)
When it’s not worth it: - As a magnesium supplement to correct deficiency, improve sleep, cramps, or any other goal. Absorption is so low that almost everything remains unabsorbed take advantage.
Honest recommendation: if you have bought oxide thinking it was the standard “magnesium,” it’s not exactly a mistake your part — marketing positions it as such. But now that you know, switch to bisglycinate or citrate next time.
How to choose the correct magnesium according to goal
The practical table to make the decision:
| Your main goal | Recommended magnesium | Alternative |
|---|---|---|
| Sleep better | Bisglycinate | Glycinate |
| Reduce anxiety or stress | Bisglycinate | Taurate |
| Muscle cramps | Bisglycinate | Citrate |
| General sports recovery | Citrate | Bisglycinate |
| Improve intestinal transit | Citrate | Oxide (occasional) |
| Fight chronic fatigue | Malate | Bisglycinate |
| Memory and concentration | L-threonate | Malate |
| Cardiovascular health | Taurate | Bisglycinate |
| Local muscle recovery | Chloride (Epsom salts) | — |
| Pregnancy and general deficiency | Bisglycinate (always consult) | — |
If you are only going to have one form at home and don’t want to think about it anymore: bisglycinate. Covers most needs, does not cause digestive discomfort, and absorption is among the best on the market.
When to combine several forms make sense
For people with specific needs, combining two forms can to be more efficient than doubling the dose of one:
- Bisglycinate (night) + malate (morning): for insomnia + chronic fatigue
- Citrate (morning) + bisglycinate (night): for athletes with slow transit and sleep problems
- Taurate + L-threonate: for older adults with cardiovascular and cognitive concern
Combinations make sense when goals do not overlap. If you only need one, a single well-chosen form works better than a cocktail.
Dose general by age and sex (reference amounts)
Recommended daily amounts (total intake, not just from the supplement) according to European guidelines:
| Group | Recommended daily intake |
|---|---|
| Adult man | 350-420 mg/day |
| Adult woman | 280-320 mg/day |
| Pregnant woman | 350-400 mg/day |
| Adolescents 14-18 | 360-410 mg/day |
| Over 60 | 350-420 mg/day |
| Athletes with high load | 400-500 mg/day |
Most magnesium should come from the diet (dark green, nuts, legumes, seeds, dark chocolate). The supplement covers the difference when the diet falls short — a very common case in the modern Western.
When magnesium is NOT the solution
Three situations where many people take magnesium looking for something that magnesium does not solve:
- Severe chronic insomnia: magnesium helps with mild sleep. Chronic insomnia has causes that require evaluation professional.
- Frequent cramps with associated symptoms (weakness, tingling): it may be magnesium deficiency, but also potassium, calcium, or vitamin B12. Tests first.
- Chronic tiredness without a clear cause: magnesium can help if there is a deficiency. If there is no deficiency, the supplement will not resolve fatigue caused by insufficient sleep, diet, hypothyroidism or other factors.
Magnesium is an effective nutrient, but it is not a universal remedy. Asking for more than it can give ends in frustration with the supplement.
Frequently asked questions
Bisglycinate covers more cases than any other form with the best digestive tolerance and high absorption. If you can only keep one one, that one.
Bisglycinate and malate yes, no problem. Citrate and chloride can cause discomfort in some people if taken on an empty stomach — better with food.
Depends on the form. Bisglycinate and glycinate: night (calming effect). calming). Citrate: morning or noon. Malate: morning (can activate). Threonate: divided into 2-3 doses throughout the day.
Yes, without interference. Some athletes take them together or at different times different without problem.
“Marine magnesium” is a commercial name; it is usually oxide extracted from sea water. The name sounds more natural but absorption remains being low because it is oxide. Don’t be guided by the origin — look at the chemical form.
For sleep and cramps: effect in a few days. For chronic fatigue or cognitive function: 4-8 weeks of consistency. If after 3 months you haven’t noticed changes, reconsider the dose or type.
Oxide except for occasional laxative use: poor absorption causes the investment is not worth it. Aspartate was popular years ago but related to excitatory effects — today it is avoided in favor of forms that are described in this guide.
No. It is a mineral, it provides zero direct calories. If you notice bloating abdominal with certain forms, it is temporary intestinal water retention (common with citrate), no fat gain.
In summary
Each type of magnesium has a purpose. The question is not “which is the best?” but “which is the best for my case?”. The goals table at the end of the “how to choose” section summarizes the decision: if you want sleep, bisglycinate; if you have transit problems, citrate; if it if what you are looking for is energy and to fight fatigue, malate; if you work on memory, L-threonate; if you are concerned about the heart, taurinate.
And as a practical rule: avoid oxide as the main supplement. It is cheap but doesn’t make the most of your money or your body.
If you have doubts about whether what you need is a magnesio o algo distinto, para qué sirve el magnesium covers when deficiency is likely and how to identify it. And si te preocupan los efectos al subir dosis, en efectos secundarios magnesium there is honest information about what is and isn’t should be expected.


Artículo redactado por...
Jorge Albert Mallabrera
Redactor especializado en fitness, recuperación muscular y bienestar.
Miguel Artín
CEO en Welbeinn · Especialista en terapias de recuperación.
Caetano
Equipo Welbeinn · Producto y protocolos de uso.
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